GHK-CU + TRETINOIN CREAM – GHK-CU + TRETINOIN + VIT C + HYALURONIC ACID + KOJIC ACID

This formula is generally safe for most skin types when used under medical supervision, but requires caution with sensitive skin. Tretinoin and kojic acid can cause irritation, especially initially. Our physicians assess your skin type during consultation and may recommend patch testing or starting with reduced frequency. Those with very sensitive skin, rosacea, or eczema may need alternative formulations.

Initial improvements typically appear within 2-3 weeks, including smoother texture and initial brightening. Significant anti-aging results become visible at 6-8 weeks, while dark spots and hyperpigmentation usually show noticeable fading within 4-8 weeks. Maximum benefits develop over 3-6 months of consistent use as collagen production increases and cellular turnover normalizes.

You'll need to modify your routine during treatment. Discontinue other retinoids, AHAs, BHAs, hydroquinone, or benzoyl peroxide to prevent over-irritation. Use only gentle, fragrance-free cleansers and moisturizers. Vitamin C serums should be avoided initially as they may interact with tretinoin. Our medical team provides specific product recommendations compatible with your treatment.

The first 2-4 weeks often involve an adjustment period called retinization. Common effects include mild redness, dryness, peeling, or temporary darkening of spots before they lighten. Some users experience initial breakouts as skin purges. These effects typically subside as tolerance builds. Start with every-other-night application and gradually increase frequency.

Yes, significantly stronger. This contains prescription-strength tretinoin (0.025-0.1%) compared to weaker retinol in retail products. The kojic acid concentration is also higher than typical cosmetic formulations. The addition of pharmaceutical-grade GHK-Cu peptide creates synergistic effects not available in consumer products. This requires medical supervision due to its potency.

Daily broad-spectrum SPF 30+ sunscreen is mandatory, as both tretinoin and kojic acid increase photosensitivity significantly. Reapply sunscreen every 2 hours when outdoors. Avoid direct sun exposure when possible, especially during peak hours. Use protective clothing and wide-brimmed hats. Discontinue use 1 week before any sun-intensive activities or vacations to prevent severe burns or pigmentation issues.